Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes in Drug Discovery and Development
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Product Description
Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P450 and similar enzymes - as well as parallel issues shaping the pharmaceutical industry - to promote the next generation of safer, more effective drugs.
Product Details
- Amazon Sales Rank: #1771807 in Books
- Published on: 2003-09-03
- Original language: English
- Dimensions: 2.51 pounds
- Binding: Hardcover
- 608 pages
Editorial Reviews
Book Info
(Fontis Media) Summarizes the latest findings on P450 and similar enzymes for promoting the next generation of safer, more effective drugs. Discusses P450 in experimental animals, bioactivation and human drug clearance, enzyme kinetics and P450 reaction phenotyping, P450 in drug-drug interactions, and non-P-450 mediated metabolism of xenobiotics.
