Product Description

“The bard of biological weapons captures
the drama of the front lines.”
-Richard Danzig, former secretary of the navy


The first major bioterror event in the United States-the anthrax attacks in October 2001-was a clarion call for scientists who work with “hot” agents to find ways of protecting civilian populations against biological weapons. In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a #1 New York Times bestseller, Richard Preston takes us into the heart of Usamriid, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the U.S. biological weapons program and now the epicenter of national biodefense.

Peter Jahrling, the top scientist at Usamriid, a wry virologist who cut his teeth on Ebola, one of the world’s most lethal emerging viruses, has ORCON security clearance that gives him access to top secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox-and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science, the smallpox virus now resides, officially, in only two high-security freezers-at the Centers for Disease Control in Atlanta and in Siberia, at a Russian virology institute called Vector. But the demon in the freezer has been set loose. It is almost certain that illegal stocks are in the possession of hostile states, including Iraq and North Korea. Jahrling is haunted by the thought that biologists in secret labs are using genetic engineering to create a new superpox virus, a smallpox resistant to all vaccines.

Usamriid went into a state of Delta Alert on September 11 and activated its emergency response teams when the first anthrax letters were opened in New York and Washington, D.C. Preston reports, in unprecedented detail, on the government’s response to the attacks and takes us into the ongoing FBI investigation. His story is based on interviews with top-level FBI agents and with Dr. Steven Hatfill.

Jahrling is leading a team of scientists doing controversial experiments with live smallpox virus at CDC. Preston takes us into the lab where Jahrling is reawakening smallpox and explains, with cool and devastating precision, what may be at stake if his last bold experiment fails.

Product Details

• Amazon Sales Rank: #734852 in Books
• Published on: 2002-10-08
• Released on: 2002-10-08
• Original language: English
• Binding: Hardcover
• 256 pages

From Amazon.com
On December 9, 1979, smallpox, the most deadly human virus, ceased to exist in nature. After eradication, it was confined to freezers located in just two places on earth: the Center for Disease Control in Atlanta and the Maximum Containment Laboratory in Siberia. But these final samples were not destroyed at that time, and now secret stockpiles of smallpox surely exist. For example, since the fall of the Soviet Union in 1991, and the subsequent end of its biological weapons program, a sizeable amount of the former Soviet Union's smallpox stockpile remains unaccounted for, leading to fears that the virus has fallen into the hands of nations or terrorist groups willing to use it as a weapon. Scarier yet, some may even be trying to develop a strain that is resistant to vaccines. This disturbing reality is the focus of this fascinating, terrifying, and important book.

A longtime contributor to The New Yorker and author of the bestseller The Hot Zone, Preston is a skillful journalist whose work flows like a science fiction thriller. Based on extensive interviews with smallpox experts, health workers, and members of the U.S. intelligence community, The Demon in the Freezer details the history and behavior of the virus and how it was eventually isolated and eradicated by the heroic individuals of the World Health Organization. Preston also explains why a battle still rages between those who want to destroy all known stocks of the virus and those who want to keep some samples alive until a cure is found. This is a bitterly contentious point between scientists. Some worry that further testing will trigger a biological arms race, while others argue that more research is necessary since there are currently too few available doses of the vaccine to deal with a major outbreak. The anthrax scare of October, 2001, which Preston also writes about in this book, has served to reinforce the present dangers of biological warfare.

As Preston eloquently states in this powerful book, this scourge, once contained, was let loose again due to human weakness: "The virus's last strategy for survival was to bewitch its host and become a source of power. We could eradicate smallpox from nature, but we could not uproot the virus from the human heart." --Shawn Carkonen

From Publishers Weekly
Never mind Ebola, the hemorrhagic disease that was the main subject of Preston's 1994 #1 bestseller, The Hot Zone. What we really should be worrying about, explains Preston in this terrifying, cautionary new title, is smallpox, or variola. But wasn't that eradicated? many might ask, particularly older Americans who remember painful vaccinations and the resultant scars. Officially, yes, nods Preston, who devotes the first half of the book to the valorous attempt by an army of volunteers to wipe out the virus (an attempt initially sparked by '60s icon Ram Dass and his Indian guru) via strategic vaccination; in 1977 the last case of naturally occurring smallpox was documented in Somalia, and today the variola virus exists officially in only two storage depots, in Russia and at the Centers for Disease Control in Atlanta (in the freezer of the title). To believe that variola is not held elsewhere, however, is nonsense, argues Preston, who delves into the possibility that several nations, including Iraq and Russia, have recently worked or are currently working with smallpox as a biological weapon. The author devotes much space to the anthrax attacks of last fall, mostly to demonstrate how easily a devastating assault with smallpox could occur here. He includes an interview with Steven Hatfill, who has received much press coverage for the FBI's investigation of him regarding those attacks; his description of meeting Hatfill, hallmarked by a quick character sketch ("He was a vital, engaging man, with a sharp mind and a sense of humor.... He was heavy-set but looked fit, and he had dark blue eyes") is emblematic of what makes this New Yorker regular's writing so gripping. Preston humanizes his science reportage by focusing on individuals-scientists, patients, physicians, government figures. That, and a flair for teasing out without overstatement the drama in his inherently compelling topics, plus a prose style that's simple and forceful, make this book as exciting as the best thrillers, yet scarier by far, for Preston's pages deal with clear, present and very real dangers.
Copyright 2002 Reed Business Information, Inc.

From Library Journal
In an account that might well be called Return of the Hot Zone, Preston sends out alarms that smallpox could reenter our midst and what's worse, in genetically engineered form.
Copyright 2002 Reed Business Information, Inc.